Fun research study for cash
http://sfbay.craigslist.org/sfc/etc/1319344674.html
---
Psychedelic Science -- Ecstasy (MDMA) Research
Date: 2009-08-12, 9:21AM PDT
Reply to: see below
Do you take MDMA and feel great for a few hours and then not so great the next day?
John Mendelson MD and his colleagues at California Pacific Medical Center Research Institute are seeking people like you to measure how taking the antidepressant citalopram might change the emotional and physical effects of MDMA.
This federally-funded study involves administration of both MDMA and citalopram in a laboratory setting.
You should be in good physical and mental health.
This is research not treatment. Compensation offered.
(415) 641-3370, ask for study 3D
* Compensation: up to $1140
* Principals only. Recruiters, please don't contact this job poster.
* Phone calls about this job are ok.
* Please do not contact job poster about other services, products or commercial interests.
hahahahahahhaha
i wonder if they provide the mdma
Alland Byallo
Nightlight Music | [KONTROL] | Forward SF
as a matter of fact, they do.
unfortunately, the study takes 5 weeks and you cannot have any other illegal drugs in your system. including medicinal cannabis. :(
*rolling for dollars FAIL.*
www.facebook.com/bird415 | www.myspace.com/bird415
www.kontrolsf.com | www.myspace.com/kontrolsf
www.afterglowsf.com | www.myspace.com/afterglowsf
if they guaranteed $1140 i'd do it.
Alland Byallo
Nightlight Music | [KONTROL] | Forward SF
sounds like an emotional nightmare to me. you take e... then anti-depressants. seems dangerous.
---------------------------------
http://kirkwoodwest.com
citalopram is a very common SSRI (serotonin reuptake inhibitor)... which, if i understand it correctly, helps prevent serotonin from being reabsorbed into the brain cells. MDA releases serotonin in the brain, right? so it seems like they're trying to figure out if taking e while also being on an SSRI will make you feel REALLY good for an extended period of time (no abrupt comedown).
it kind of makes since, at least in my bwraindamaged noggin.
from what i've read, the SSRI+MDMA combination has been researched quite a bit but still isn't super well understood. generally, administering an SSRI with MDMA is reported to actually dampen the subjective effects. MDMA works by reversing the action of the serotonin re-uptake valves, i.e. it connects to the spot where serotonin is normally reabsorbed and actually pulls the serotonin back out into your brain, so you end up with a bunch more than usual floating around. SSRIs, on the other hand, connect to those same re-uptake valves, but rather than pulling serotonin out of them, they simply block the serotonin that's already in your brain from being reabsorbed, letting it build up slowly over time. SSRIs have a stronger binding affinity to those valves than MDMA does, so if taken at the same time they actually fill up all the slots and prevent the MDMA from doing its thing to the full extent (depending upon the balance of how much SSRI vs. MDMA is present).
i'd guess the aim of the study is to figure out how to combine the two in such a way as to "smooth out" MDMA's serotonin response, so it's not a big spike followed by a big crash, but rather a gradual change. that would mean a lower risk of short-term depression, making it much more practical and ethical for medical applications (i.e. therapy for PTSD or emotional trauma).
i have no idea why i just went into so much detail on this.
but i'm with kirkwood on this one. the idea of being stuck in a weird hospital environment surrounded by strangers for an extended period of time, being given a combination of things... fully supportive of the research, but not for me.
http://www.house-heads.com